The Difference


The Different Angle of Science



Different from lasers or IPL, which penetrate the skin from the outside-in; the Medgene DUOS treatment procedure bypasses the skin surface, delivers energy into the deep tissues and muscles where collagen lives. Medgene DUOS involves penetrating energy to stimulate collagen production in the deep and sub-dermal layer, which results in minor injury to that tissue. As the tissue heals, it increases collagen and as the collagen fibers shorten on heal, a tightening effect is seen on the tissue.

Tissue at the target point is heated to ~65°C, Thermal Heat create wounds and cellular friction - which also in turn promotes healing, immediately contracts collagen and stimulates a rapid production. Over the next 3 to 6 months, the healing response stimulates long-term tissue and leads to further lifting and tightening, with results that can last years.


The Duo-Layer Results

The Medgene DUOS offer two level of cutaneous penetration, the superficial level and the SMAS level. In general, the areas with the thinnest skin, such as the neck and periocular area, should be treated with superficial depth probes; the brow and temple should be treated with superficial and deeper probes; and cheek and submental skin is best treated with the deepest 4-MHz 4.5-mm probe followed by additional treatment with a superficial probe.

  • Thermal Effect
  • Collagen Remodeling
  • Tightening & Wrinkle Treatment
  • Thermal Coagulation
  • SMAS Contraction
  • Face Lifting and Tightening



The 3mm is able to penetrate deeper into tissue than its nonsurgical predecessors in an effort to affect superior tissue tightening and longevity of results by selectively targeting the superficial muscular aponeurotic system (SMAS). The SMAS lies deep to the subcutaneous fat, envelops the muscles of facial expression, and extends superficially to connect with the dermis. The SMAS layer is composed of collagen and elastic fibers similar to the dermal layer of the skin; however, it has more durable holding property and less delayed relaxation after lifting procedures than skin alone. Thus, the SMAS is a desirable target for noninvasive skin tightening procedures.